Adverse Pathologic Features Following Prostatectomy for Favorable High-Risk Versus Other High-Risk Prostate Cancer: Implications for Choice of Local Therapy
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چکیده
منابع مشابه
Brachytherapy boost and cancer-specific mortality in favorable high-risk versus other high-risk prostate cancer.
PURPOSE Recent retrospective data suggest that brachytherapy (BT) boost may confer a cancer-specific survival benefit in radiation-managed high-risk prostate cancer. We sought to determine whether this survival benefit would extend to the recently defined favorable high-risk subgroup of prostate cancer patients (T1c, Gleason 4 + 4 = 8, PSA < 10 ng/ml or T1c, Gleason 6, PSA > 20 ng/ml). MATERI...
متن کاملRadical Prostatectomy in High Risk Prostate Cancer
Prostate cancer is the leading cancer diagnosis in men, and the second cuase, after lung cancer, of cancer death in men in the U.S. Worldwide is the fourth most common cancer in men with variable incidence and mortality rates, based on geographic regions (1). In Europe is the most common solid tumor, with an incidence of 214 cases per 1000 men, outnumbering the lung and colorectal cancers, and ...
متن کاملRadical prostatectomy in high-risk prostate cancer.
One consistent finding in the studies regarding treating men with prostate cancer is that men with high-risk disease have the most to gain from treatment with curative intent. Men with high-risk or locally-advanced prostate cancer require treatment to the primary cancer or risk dying prematurely from their disease. Increasingly, combined androgen deprivation therapy + radiation treatment is see...
متن کاملNeoadjuvant hormone therapy following treatment with robotic-assisted radical prostatectomy achieved favorable in high-risk prostate cancer
PURPOSE Patients with a high risk of prostate carcinoma typically have higher rates of positive surgical margins and biochemical failure following radical prostatectomy and adjuvant hormone therapy. In this study, we assessed the effects of neoadjuvant hormone therapy (NHT) on prostate carcinoma in high-risk patients following robotic-assisted radical prostatectomy (RARP). METHODS This retros...
متن کاملCurrent Status of Radical Prostatectomy for High-Risk Prostate Cancer
Despite the wide application of prostate-specific antigen-based screening leading to a profound stage migration in prostate cancer (PC), a significant percentage of men are still being diagnosed with clinically high-risk disease that requires aggressive treatment. Optimal management in these patients remains challenging, and strong advocates for radical prostatectomy (RP), radiotherapy, androge...
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ژورنال
عنوان ژورنال: International Journal of Radiation Oncology*Biology*Physics
سال: 2016
ISSN: 0360-3016
DOI: 10.1016/j.ijrobp.2016.06.1265